Mysterious; not sympathomimetic; may well boost dopamine levels within the brain by binding into the dopamine transporter and inhibiting dopamine reuptake
Youngsters and children youthful than seventeen a long time of age—Use and dose needs to be based on your health practitioner.
cenobamate will increase the degree or outcome of modafinil by influencing hepatic enzyme CYP2C19 metabolism. Modify Therapy/Monitor Closely. Contemplate a dose reduction of CYP2C19 substrates, as clinically acceptable, when utilized concomitantly with cenobamate.
Watch Intently (1)modafinil will enhance the degree or influence of diazepam intranasal by affecting hepatic enzyme CYP2C19 metabolism. Use Warning/Keep an eye on. Solid or average CYP2C19 inhibitors might lower charge of diazepam elimination, thus rising adverse reactions to diazepam.
Modafinil is often taken Each and every morning to stop daytime sleepiness, or 1 hour before the commence of a work change to deal with get the job done-time sleep Issues.
modafinil will raise the level or impact of diazepam intranasal by impacting hepatic enzyme CYP2C19 metabolism. Use Caution/Keep track of. Sturdy or average CYP2C19 inhibitors could minimize charge of diazepam elimination, thereby raising adverse reactions to diazepam.
modafinil will reduce the extent or outcome of diazepam buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Robust or moderate CYP3A4 inducers may well boost level of diazepam elimination; thus, efficacy of diazepam can be lessened.
When the full choice of modafinil’s opportunity drug interactions is not really nonetheless completely identified, a variety of early reports have documented prospective adverse interactions between modafinil and the following prescription drugs along with other compounds [seventy eight, 79]:
This medication may well have an impact on your focus, functionality, or may possibly conceal signals you are weary. You might get dizzy. Don't generate, use machinery, or do everything that desires mental alertness right until you know how this drug impacts you.
carbamazepine will decrease the level or outcome of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
rifabutin will lessen the level or outcome of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
modafinil boosts levels of eluxadoline by impacting hepatic enzyme click here CYP2C19 metabolism. Use Caution/Keep an eye on. As a precautionary measure as a result of incomplete info on the metabolism of eluxadoline, use caution when coadministered with sturdy CYP2C19 inhibitors.
When you are allergic to modafinil; any section of this drugs; or almost every other prescription drugs, foods, or substances. Explain to your medical professional with regards to the allergy and what signs you had.
No unique dose adjustment recommended when tofacitinib coadministered with strong CYP2C19 inhibitors; lower tofacitinib dose if coadministered with the two average CYP3A4 and strong CYP2C19 inhibitors .